These cells contain the ? 1 adrenergic receptors, in that one component of the mechanism hypotensive action of ? blockers is to reduce the secretion of re-Nina. Drug is prescribed 2-3 times a day (tabletkiretard - 1 times a day) at Al-arterial hypertension, vasospastic angina and supraventricular tachyarrhythmias. To reduce tachycardia dihydropyridine calcium Physician Assistant blockers recommend combined with ? blockers. The drug was appointed interior, the duration of 68h. In addition, these drugs have a weak bronchodilator, tocolytic, and antiplatelet противоатеросклеротическое abjure Among calcium channel blockers produce dihydropyridines, phenylalkylamine and benzotiazepiny. Magnesium sulfate for intramuscular or intravenous injection causes a marked hypotensive effect, which is associated with myotropic vasodilating action, as well as the depressing effect on the vasomotor center and the transfer of excitation sympathetic ganglia. In addition, inhibition of ACE eliminated inactivating effect of ACE abjure bradykinin - bradykinin level rises. In general, the body under the action of nifedipine reduced blood pressure and in this connection there is a abjure tachycardia. In this regard, calcium channel blockers crystals act mainly on the heart and arteries vessels (effects on venous vessels slightly, so the blockers calcium channel tsievyh practically do not cause orthostatic hypotension). Verapamil (izoptin) slowed and weakened contraction of the heart, makes it difficult to atrio-ventricular conduction, expands small coronary vessels (increasing the volume rate of coronary blood flow), moderately abjure peripheral artery disease. Nimodipine - vysokolipofilny calcium channel blocker, easily penetrates the blood-brain barrier arises. For a systematic treatment of hypertension recommend only long-acting preparations of nifedipine (Tabletkiretard), which operate 24 hours and set 1 time per day (drugs, you're a short-acting with a systematic use increases mortality of patients, apparently due to the vibrations of blood pressure). ACE inhibitors abjure the formation of angiotensin II. In Unlike dihydropyridines these drugs for systemic effect weakening of the poop, and slowed heart beat difficult atrioventricular conduction. In combination with reserpine, and hydrochlorothiazide is a member of the tablets "Adelfan - Ezidreks. The drug is useful to combine with substances that reduce the influence of the sympathetic innervation (? blockers, reserpine), and diuretics. Magnesium sulfate is not recommended to use during childbirth, as the drug-running lablyaet reduction myometrium. Side effects of hydralazine: dizziness, headache, flushing a sample, nasal congestion, tachycardia, postural hypotension, worsening ischemic heart disease, nausea, vomiting, diarrhea, skin rashes, pair-paths, proteinuria, leukopenia, anemia, thrombocytopenia. As the antihypertensive drug verapamil is shown in patients with soput-corresponding coronary insufficiency, cardiac arrhythmias. Diltiazem in comparison with the dihydropyridines are abjure of degree affects the heart and less from the arterial abjure as compared with verapamil has a greater effect on blood vessels and less on the heart.
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